"NAD+ Infusion: The Latest Trendy Anti-Aging Treatment or Just Hype?"

NAD+ infusion therapy has swept through Hollywood and wellness circles, with celebrities like Hailey Bieber and influencers touting its anti-aging benefits. But is this trendy treatment backed by science, or is it just another fad? Let's dive into the world of NAD+ infusions, exploring the hype, the science, and the potential risks.



The Hype: NAD+ as the Fountain of Youth

NAD+ infusion therapy is marketed as a miracle cure for aging, promising to boost energy, improve cognitive function, and even reverse the effects of aging. Celebrities and wellness enthusiasts are flocking to clinics for routine NAD+ infusions, hoping to turn back the clock on aging. Rana Good, a New York-based journalist, decided to try NAD+ after hearing that it could boost her energy levels. "It was billed as 'the fountain of youth.' It’s supposed to restore your energy and well-being," Good told Verywell.

But is the hype justified? Let's take a closer look at the science behind NAD+ infusion therapy.

The Science: What Does NAD+ Actually Do?

NAD+, or nicotinamide adenine dinucleotide, is a coenzyme that plays a crucial role in energy metabolism, stress response, and DNA repair. As we age, our NAD+ levels naturally decline, which has been linked to aging-related diseases. Some mice studies suggest that NAD+ supplements could replenish NAD+ levels, but the benefits of NAD+ therapy in humans remain unclear.

Many of the human trials on NAD+ have been small, involving 30 or fewer participants. Sumeet Deogan, PharmD, an emergency medicine clinical pharmacist at MedStar Georgetown University Hospital, told Verywell, "I’m not gonna yuck anyone’s yum when it comes to what makes you feel good. But I don’t think there’s much evidence to support it."

The Risks: Is NAD+ Infusion Safe?

NAD+ IV therapy is marketed as an anti-aging miracle that can help with everything from joint pain to long COVID. However, these claims have not been validated by the FDA. Richina Bicette-McCain, MD, an assistant professor of emergency medicine at Baylor College of Medicine, warned, "[T]here is no guarantee that the drug is safe nor is there any certainty that the drug will have whatever effect that is being advertised."

In 2021, the FDA warned that some IV and hydration clinics used drug products prepared in unsanitary conditions. Getting an IV, especially in an environment that isn’t clean or safe, can increase the chance of an infection. IV fluids can also sometimes leak, harming the skin or tissues.

The Cost: Is NAD+ Therapy Worth the Money?

Each NAD+ infusion session could cost hundreds of dollars and take up to four hours. Some clinics recommend getting the treatments weekly or monthly. But is it worth the investment? Bicette-McCain said, "Realistically, I can’t say for sure that there are any benefits that a patient can expect from these infusions because the research isn’t robust enough."

The Verdict: Should You Try NAD+ Infusion Therapy?

NAD+ infusion therapy may offer potential benefits such as increased energy, improved cognitive function, and anti-aging effects. However, the lack of robust scientific evidence, potential side effects, cost, safety concerns, and the possibility of a placebo effect make it a risky investment. Individuals considering NAD+ infusion therapy should consult with a trusted healthcare provider and weigh the potential benefits against the risks before making a decision.

In conclusion, while NAD+ infusion therapy may offer potential benefits, the lack of robust scientific evidence, potential side effects, cost, safety concerns, and the possibility of a placebo effect make it a risky investment. Individuals considering NAD+ infusion therapy should consult with a trusted healthcare provider and weigh the potential benefits against the risks before making a decision.